No. 84 - Immune / Inflammaging / Gut Barrier

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Immune Function
Immune Function
Gut Barrier
Gut Barrier
Health Aging Support
Health Aging Support

Made for immune support, gut wellness, and seasonal resilience. Formulated to nourish the microbial ecosystem behind steady everyday balance — through changing seasons, environments, and daily rhythms.

Dial In Your Microbiome Strategy

Adjust the sliders to personalize your microbiome strategy - from gradual foundational support to a more comprehensive, longer-term approach.

How often do you experience sluggish immune response or difficulty recovering from everyday stressors? 3
Rarely Frequently
How long have you been experiencing this? 3
Months Years
Your Strategy
Targeted Optimization
Your Protocol
8–12 weeks, daily
Complete Protocol
3 bottles
Complete Protocol Now

Brief Discussion of MAIOME's No. 84

Listen to a short conversation on how No. 84 was designed to help support your immune system and gut barrier integrity.
0:00 0:00

No. 84: Precision Feeding. Precision Limiting. Nothing Left to Chance.*

Designed to influence specific microbial pathways by promoting beneficial bacteria and inhibiting less favorable strains—helping create a more stable, resilient microbiome environment.

↓Beneficial Bacteria*

Feeds microbes associated with beneficial physiological functions

↓Disruptive Bacteria*

Helps limit microbes associated with imbalance*

↓Microbiome Stress*

Supports a healthier internal environment by reducing ecosystem strain*

↑Overall Resilience*

Supports a more adaptable and stable gut ecosystem*

The Science That Makes MAIOME No. 84 So Unfair

(In The Best Way)
1
Builds a Gut Wall Your Immune System Can Actually Work Behind*
Precision prebiotic compounds reinforce gut barrier integrity so your first line of immune defense stops leaking and starts performing.
2
Addresses the Microbial Imbalances That Keep Your Immune System Stuck*
No. 84's precision prebiotic complex is formulated to shift your gut environment toward a bacterial balance that supports a healthy, well-regulated immune response.*
3
Trains Your Immune System to Know the Difference Between Threat and Noise*
Promoting Bifidobacterium and Lactobacillus recalibrates immune signaling so your body stops overreacting and starts responding with precision.*
4
Supports Your Body's Natural Defenses Against the Effects of Time*
No. 84 is precision-formulated to promote the bacterial balance associated with healthy immune resilience, helping your body maintain its edge as you age.*

Not sure where to start? Take our MyBiome Match™ quiz

Your Microbiome Feels The Love

ON DAY ONE

Day 1

YOUR GUT MICROBIOME BEGINS SHIFTING TOWARD BALANCE. Cranberry extract and grape seed extract immediately begin suppressing Clostridium and Enterobacteriaceae — the bacteria whose LPS byproducts leak through the gut wall and trigger chronic immune activation.

Day 30

A HEALTHIER GUT ENVIRONMENT STARTS TO TAKE HOLD. Clostridium and Enterococcus populations decline as Lactobacillus and Bifidobacterium grow, producing lactic acid that acidifies the gut and inhibits pathogenic colonization.

Day 90

YOUR GUT BARRIER SUPPORTS HEALTHY, LASTING CALIBRATED IMMUNE FUNCTION. With less bacterial LPS crossing the gut barrier, the chronic immune activation driving inflammaging begins to quiet and the immune system becomes more appropriately calibrated.

Day 180

YOUR GUT BARRIER INTEGRITY AND IMMUNE RESILIENCE ARE ACTIVELY OPTIMIZING. Six months of barrier-supportive bacterial growth has strengthened tight junction proteins, mitigating systemic endotoxin load, and produced downstream improvements for long term immune resilience.

Day 365

RESILIENT MICROBIOME AND LASTING INNER BALANCE ARE YOUR NEW FOUNDATION. The structural root of inflammaging — a permeable, dysbiotic gut — has been systematically addressed, and inner balance is the durable result.

4 Science-Backed Ingredients To Supercharge Your Microbiome

Cranberry Extract 4:1
Modulation Selectivity Adhesion

Functions as a polyphenol-based prebiotic that selectively promotes beneficial bacteria such as Bifidobacterium and Lactobacillus while limiting the ability of less favorable microbes to adhere and proliferate within the gut environment.

Acai Extract 4:1
Activation Signaling Biotransformation

Provides polyphenol compounds that activate beneficial bacteria such as Bifidobacterium and support microbial signaling pathways, helping enrich the gut environment in favor of bacteria linked to immune balance and gut barrier resilience.

Chitosan
Binding Filtration Selectivity

Acts as a functional substrate and microbial filter that supports beneficial bacteria such as Lactobacillus while helping limit less favorable strains. Through its unique binding properties, it works synergistically with accompanying prebiotics to enhance microbial selectivity—supporting a more stable and resilient gut ecosystem.

GrapeSeed Extract 95%
Barrier Integrity Antioxidant Support Gut-Immune Axis

Functions as a precision polyphenol modulator that supports the gut-immune axis by promoting the bacterial populations associated with healthy gut barrier integrity — particularly Bifidobacterium and Lactobacillus — while discouraging the less favorable strains whose byproducts can compromise the mucosal barrier. Its proanthocyanidin compounds provide direct antioxidant support to the gut lining, reinforcing the structural foundation that immune resilience is built on.