No. 25 - Cardiovascular / Antioxidant

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Cardiovascular Function
Cardiovascular Function
Antioxidant
Antioxidant
Cardiac Tissue Support
Cardiac Tissue Support

Supports vascular tone and antioxidant activity through microbial ecosystem modulation. Ideal for foundational resilience in circulation and cellular performance.

Dial In Your Microbiome Strategy

How much do you focus on maintaining healthy cardiovascular function? 3
A Little A Lot
How long has this been a concern for you? 3
Months Years
Your Strategy
Targeted Optimization
Your Protocol
8–12 weeks, daily
Complete Protocol
3 bottles
Complete Protocol Now

Brief Discussion On MAIOME's No. 25

Listen to this short conversation around how No. 25 was designed specifically to support various aspects of cardiovascular health.
0:00 0:00

No. 25: Precision Feeding. Precision Limiting. Nothing Left to Chance.*

Designed to influence specific microbial pathways by promoting beneficial bacteria and inhibiting less favorable strains — helping create a gut environment that supports healthy cardiovascular function and antioxidant defense.

↑Cardiovascular-Supporting Bacteria*

Feeds microbes associated with healthy vascular function and antioxidant metabolite production

↓Oxidative Stress-Associated Bacteria*

Helps limit microbes associated with compromised cardiovascular function and reduced antioxidant capacity

↓Cardiometabolic Microbiome Stress*

Supports a healthier internal environment by reducing the microbial contributors to oxidative burden and compromised heart function

↑Cardiovascular Resilience*

Supports a more stable gut ecosystem oriented toward lasting heart health and antioxidant protection

Burn more calories even at rest.

The Science That Makes MAIOME No. 25 So Unfair

(In The Best Way)
1
Supports the Cardiometabolic Microbiome — The Gut-Heart Connection Science Is Only Beginning to Map*
The cardiometabolic microbiome refers to the specific bacterial populations that influence cardiovascular function through metabolite production, oxidative balance, and lipid metabolism. No. 25 promotes Cloacibacillus, Akkermansia, and Bacteroidetes — populations associated with a healthier cardiometabolic microbial profile.*
2
Targets the Bacterial Populations Associated With Oxidative Burden*
Clostridium, Anaeroglobus, and Firmicutes produce metabolites that place oxidative stress on the cardiovascular system when present in excess. No. 25 is precision-formulated to discourage these populations while promoting the microbial conditions that support healthy antioxidant defense from within the gut.*
3
Supports Healthy Lipid Metabolism Through the Gut-Heart Axis*
The gut-heart axis describes the pathway through which microbial metabolites influence cardiovascular function — including lipid metabolism, vascular tone, and antioxidant capacity. By promoting Eggerthella and Prevotella, No. 25 supports the bacterial populations associated with healthier lipid metabolite profiles and more robust cardiovascular function.*
4
Builds a Heart-Supportive Gut Ecosystem Designed to Last*
Trans-resveratrol, pomegranate extract, and chitosan — the precision prebiotic complex in No. 25 — work together to shift the gut environment toward a bacterial balance associated with healthy cardiovascular function and lasting antioxidant protection. It's not a heart supplement. It's a microbiome protocol with your heart in mind.*

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Your Microbiome Feels The Love

ON DAY ONE

Day 1

YOUR GUT MICROBIOME BEGINS SHIFTING TOWARD A HEART-SUPPORTIVE STATE. Trans-resveratrol and pomegranate extract immediately begin discouraging Clostridium, Anaeroglobus, and Firmicutes — bacterial populations associated with oxidative stress and compromised cardiovascular function — while beginning to nourish a more heart-supportive microbial environment.

Day 30

A CARDIOVASCULAR-SUPPORTIVE GUT ENVIRONMENT STARTS TO TAKE HOLD. As Enterobacteriaceae and Subdoligranulum decline, Cloacibacillus and Akkermansia grow — producing metabolites that support healthy vascular function and contribute to a more robust antioxidant environment in the gut.

Day 90

YOUR GUT SUPPORTS HEALTHY CARDIOVASCULAR FUNCTION AND ANTIOXIDANT DEFENSE. With populations associated with oxidative burden receding, the gut begins actively contributing the antioxidant signaling and metabolic support that healthy cardiac tissue depends on.

Day 180

YOUR CARDIOVASCULAR MICROBIOME IS ACTIVELY OPTIMIZING. Six months of targeted rebalancing has strengthened Prevotella, Bacteroidetes, and Eggerthella — populations linked to healthy lipid metabolism and durable antioxidant protection at the tissue level.

Day 365

RESILIENT CARDIOVASCULAR HEALTH IS YOUR NEW FOUNDATION. The microbial imbalances that contributed to oxidative stress and compromised cardiovascular function have been systematically addressed. Healthy heart function and lasting antioxidant defense are the durable result.

5 Science-Backed Ingredients That Support the Cardiometabolic Microbiome

Trans-Resveratrol (Polygonum Cuspidatum Extract 98%)
Antioxidant Support Modulation Cardiovascular SIRT1

One of the most studied polyphenols in cardiovascular research, resveratrol functions as both a microbiome modulator and a direct antioxidant contributor. Discourages Clostridium and Anaeroglobus — populations associated with oxidative burden — while supporting the microbial conditions linked to healthy vascular function and antioxidant metabolite production through the gut-heart axis.

Pomegranate Extract 40%
Biotransformation Antioxidant Selectivity

Pomegranate's polyphenols — including ellagitannins — are biotransformed by gut bacteria into urolithins, a class of compounds that support healthy antioxidant defense and are produced exclusively through microbial metabolism. No. 25 promotes the bacterial populations best equipped to perform this biotransformation — unlocking pomegranate's full cardiovascular-supportive potential from within the gut.

Chitosan
Binding Filtration Lipid Metabolism Support

A functional fiber with unique binding properties that support healthy lipid metabolism within the gut environment. Works synergistically with the polyphenol compounds in No. 25 to enhance microbial selectivity — creating a gut ecosystem more oriented toward cardiovascular health and lasting antioxidant protection.

Galactooligosaccharide
Colonization Cardiometabolic Support Resilience

Selectively nourishes Cloacibacillus, Prevotella, and Akkermansia — the cardiometabolic microbiome populations that No. 25 is designed to support. By building a robust foundation of beneficial bacteria, galactooligosaccharide ensures the broader gut ecosystem is oriented toward healthy cardiovascular function and sustained antioxidant defense.

Turmeric Powder
Modulation Gut-Heart Axis Selectivity

Functions as a precision microbiome modulator that discourages Firmicutes and Subdoligranulum while supporting the gut-heart axis bacterial populations associated with healthy cardiovascular function. Works synergistically with resveratrol and pomegranate extract to create a comprehensive cardiometabolic microbiome support system.

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